Dietary vs. Meso-zeaxanthin

Orange Paprika Pepper
All Zeaxanthin Is Not Created Equal

Unlike dietary Zeaxanthin, meso-zeaxanthin is a synthetic ingredient not found in the U.S. daily diet, but instead created from a harsh chemical modification of a crude marigold extract. No meso-zeaxanthin publications exist that demonstrate it has been tested by itself without other carotenoids, so any beneficial effects are unknown. This is also true regarding whether Macular Pigment Optical Density (MPOD) can actually be increased by meso-zeaxanthin alone.

Additional Information

  • 3-4 human meso-zeaxanthin supplementation reports concur that there is poor uptake of meso-zeaxanthin into the blood.
  • The AREDS 2 clinical trial used only dietary Zeaxanthin, not meso-zeaxanthin in its government sponsored trial.
  • Meso-zeaxanthin is currently imported from a group of suppliers in India, China, and Mexico – none of which have FDA oversight.

View our scientific support. For additional questions, contact EyePromise at
or call 1-866-833-2800.